About Karmela Miklić

Karmela Miklić

Senior laboratory engineer

karmela.miklic@medri.uniri.hr

Karmela has been employed at the University of Rijeka Faculty of Medicine since 2004. She obtained her BSc degree in Medical-laboratory Diagnostics from the University of Rijeka in 2001 and completed her internship at the Clinical Hospital Centre Rijeka in 2003.

She is specialized in numerous laboratory techniques, including immunisation with different type of antigens, cell fusion and parental screening, cloning and subcloning of hybridoma with ELISA screening, monoclonal antibody selection and cryogenic vial preservation, hybridoma isotyping, large scale monoclonal antibody production, concentration and buffer exchange after purification, determination of protein concentration, cultivation of different cell lines and transfectants, preparation of cell lysates (for screening/immunization).

Selected Publications:

    1. Cokarić Brdovčak M, Materljan Franki J, Šustić M, Miklić K, Medved M, Gaćina L, Ružić T, Jonjić S, Brizić I, Krmpotić A. Cytomegalovirus-Based Viral Vectors Elicit Robust Systemic and Tissue-Resident Immune Response Against SARS-CoV-2 Antigens. European Journal of Immunology. 2026.
    2. Kučan Brlić, P., Bellulovich, E., Golemac, M., Jakšić, A., Markić, D., Miklić, K., Malić, S., Babarović, E., Đorđević, G., Šupak Smolčić, V., Lisnić, B., Tsukerman, P., Cinamon, G., Jonjić, S., Lenac Roviš, T. High PVR protein expression marks clear cell renal cell carcinoma with metastatic spread. Frontiers in Immunology. 2026.
    3. Brlić Kučan, P, Pavletić M, Lerga M, Krstanović F, Pribanić Matešić M, Miklić K, Malić S, Mikša L, Pajcur M, Peruč D, Schubert M, Bertoglio F, Arapović J, Protić A, Šustić A, Milošević M, Šain L, Jonjić S, Jurani Lisnić V, Brizić I. SARS-CoV-2 Spike and Nucleocapsid Antibody Response in Vaccinated Croatian Healthcare Workers and Infected Hospitalized Patients: A Single Center Cohort Study. Viruses. 2022.
    4. Kalfopoulou E, Laverde D, Miklic K, Romero-Saavedra F, Malic S, Carboni F, Adamo R, Lenac Rovis T, Jonjic S, Huebner J. Development of Opsonic Mouse Monoclonal Antibodies against Multidrug-Resistant Enterococci. Infection and Immunity. 2019.
    5. Gur C, Ibrahim Y, Isaacson B, Yamin R, Abed J, Gamliel M, Enk J, Bar-On Y, Stanietsky-Kaynan N, Coppenhagen-Glazer S, Shussman N, Almogy G, Cuapio A, Hofer E, Mevorach D, Tabib A, Ortenberg R, Markel G, Miklic K, Jonjic S, Brennan CA, Garrett WS, Bachrach G, Mandelboim O. Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack. Immunity. 2015.

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