About Astrid Krmpotić

astrid-krmpotic

Astrid Krmpotić, MD, PhD

Full professor

astrid.krmpotic@medri.uniri.hr

Astrid Krmpotić, M.D., Ph.D., is a full professor in the Department of Histology and Embryology at the University of Rijeka, Faculty of Medicine. She graduated from the University of Zagreb Faculty of Medicine in 1991, completed a Master's degree in 1998, and obtained her Ph.D. at the University of Rijeka in 2001.

Professor Krmpotić has been the principal investigator (PI), co-PI, or collaborator on numerous competitive research projects, including those supported by the Croatian Science Foundation, Howard Hughes Medical Institute, the National Institutes of Health (USA), the European Regional Development Fund, and the Swiss-Croatian Cooperation Programme.

For her outstanding scientific work, she has received several awards, including the Croatian National Annual Prize for Science. To date, she has published 68 scientific papers and five book chapters, primarily focusing on virology and immunology.

Selected Publications:

    1. Brdovčak MC, Materljan J, Šustić M, Ravlić S, Ružić T, Lisnić B, Miklić K, Brizić I, Matešić MP, Lisnić VJ, Halassy B, Rončević D, Knežević Z, Štefan L, Bertoglio F, Schubert M, Čičin-Šain L, Markotić A, Jonjić S, Krmpotić A. ChAdOx1-S adenoviral vector vaccine applied intranasally elicits superior mucosal immunity compared to the intramuscular route of vaccination. European Journal of Immunology. 2022.
    2. Železnjak J, Lisnić VJ, Popović B, Lisnić B, Babić M, Halenius A, L'Hernault A, Roviš TL, Hengel H, Erhard F, Redwood AJ, Vidal SM, Dölken L, Krmpotić A*, Jonjić S*. The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors. Journal of Experimental Medicine. 2019. *co-senior authors
    3. Krmpotić A, Hasan M, Loewendorf A, Saulig T, Halenius A, Lenac T, Polić B, Bubić I, Kriegeskorte A, Pernjak-Pugel E, Messerle M, Hengel H, Busch D, Koszinowski UH, Jonjić S. NK cell activation through the NKG2D ligand MULT-1 is selectively prevented by the glycoprotein encoded by mouse cytomegalovirus gene m145. Journal of Experimental Medicine. 2005.
    4. Krmpotić A, Busch D, Bubić I, Gebhardt F, Hengel H, Hasan M, Scalzo A, Koszinowski UH, Jonjić S. MCMV glycoprotein gp40 confers virus resistance to CD8+ T cells and NK cells in vivo. Nature Immunology. 2002.
    5. Krmpotić A*, Messerle M*, Crnković-Mertens I, Polić B, Jonjić S, Koszinowski UH. The immunoevasive function encoded by the mouse cytomegalovirus gene m152 protects the virus against T cell control in vivo. Journal of Experimental Medicine. 1999. *joint 1st authorship

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